Diffusion Theory for the Infection Pathway of Virus in a Living Cell
Identifiers and Pagination:Year: 2018
First Page: 1
Last Page: 7
Publisher Id: TOPROCJ-9-1
Article History:Received Date: 10/5/2017
Revision Received Date: 27/10/2017
Acceptance Date: 13/1/2018
Electronic publication date: 28/02/2018
Collection year: 2018
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The infection pathway of virus in living cell is of interest from the viewpoint of the physics of diffusion.
Here, recent developments about a diffusion theory for the infection pathway of an adeno-associated virus in cytoplasm of a living HeLa cell are reported.
Theories and Results:
Generalizing fractional kinetics successfully modeling anomalous diffusion, a theory for describing the infection pathway of the virus over the cytoplasm is presented. The statistical property of the fluctuations of the anomalous-diffusion exponent is also discussed based on a maximum-entropy-principle approach. In addition, an issue regarding the continuum limit of the entropy introduced in the approach is carefully examined. The theory is found to imply that the motion of the virus may obey a scaling law.